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Drugs now rank second after hospitals in terms of share of total health care spending,
having overtaken spending on physicians in 1997. The share of total spending going to
drugs rose from 9.5 percent in 1985 to 16.2 percent in 2002. Spending on drugs is expected
to hit 16.7 percent of total health care spending in 2004, while spending on physicians will
be just 12.9 percent.3
The rapid rise in drug costs is primarily due to the ongoing substitution of newer, more
expensive drugs in place of existing, less expensive products. The newer drugs, in the
majority of cases, have no added benefit. Of the 117 drugs with new ingredients introduced
in Canada between 1998 and 2002, only 15 provided a substantial improvement over
existing drugs.4 The rest are “me-too” drugs that offer little or no therapeutic advances over
existing therapies but are responsible for 80 percent of the increased expenditure on drugs.5
Aggressive advertising by drug companies drives consumption of these me-too drugs.6
Apart from advertising directly to consumers, drug companies spend approximately
$30,000 per year for every doctor in Canada on drug samples, sales rep contact,
conferences, trips and giveaways.7 The influence of pharmaceutical companies on research,
education and clinical practice has also been widely documented.8 Both patients and
doctors are influenced by the onslaught,9 with the result that drug costs are skyrocketing
but health outcomes are not necessarily improving.
In an essay appearing March 17 in The Lancet, Franco Benazzi, MD, PhD, writes about a common but poorly recognized form of bipolar disorder, called bipolar disorder II.
Because the disorder is so often misdiagnosed, patients are often wrongly treated with antidepressants alone, which can make the problem worse, the professor of psychiatry tells WebMD.
"These patients need to be on mood-stabilizing drugs, and if depression persists an antidepressant can be added," Benazzi says. "Treating these patients with antidepressants alone can actually increase the manic episodes and worsen the disorder."
GABA (gamma-aminobutyric acid) is a natural calming agent. It is one of the brain’s most important regulators of proper function and neurotransmission. It appears that many people with anxiety, insomnia, epilepsy, and other brain disorders do not manufacture sufficient levels of GABA. While many drugs work by increasing the effects of GABA in the brain, they may have side effects, addictive properties, or may not be suitable for long-term use, whereas natural GABA is both safe and effective–without any known side effects.Link
Calm and Focused
Studies with synthetic GABA have shown that it does not cross the blood-brain barrier very well, leading to the assumption that GABA found in the brain was manufactured there and that supplemental GABA would not increase levels of GABA in the brain. That appears to be the case with synthetic GABA, but not with GABA naturally manufactured from Lactobacillus hilgardii.
Research has shown that GABA increases the production of alpha brain waves (a state often achieved by meditation, characterized by being relaxed with greater mental focus and mental alertness) and reduces beta waves (associated with nervousness, scattered thoughts, and hyperactivity).
In Japan GABA is a popular ingredient in functional foods, beverages, and dietary supplements designed to produce mental and physical relaxation without drowsiness. The most popular applications of GABA are found in chocolate and coffee beverages. It is particularly helpful in counteracting the effects of caffeine.
GABA is fast acting. Generally, the effects are felt within 15 minutes and can last from four to six hours.
