Tranquillizers: They can kill you fast...or kill you slow

Tranquilizers can kill you fast - or kill you slow. They deplete glutathione and cause premature aging. Doctors should not just give pills for anxiety without proper diagnosis of underlying physical conditions - nor for extended periods of time - creating "accidental addicts", morbidity and mortality.

Heath Ledger, star of “Brokeback Mountain”, died in 2008 of a prescription cocktail of anti-anxiety medications, pain killers and an antihistamine. ABC News states, “According to the medical examiner’s office, Ledger took “prescribed therapeutic doses … or less” of each medication he ingested…”

The cocktail consisted of -
Oxycodone – Pain Medication
Hydrocodone – Pain Medication
Diazepam (Valium) – Anti-Anxiety Medication
Alprazolam (Xanax and Niravam) – Anti-Anxiety Medication
Doxylamine – Antihistamine

Have you been given a benzodiazepine as "medicine" for an undiagnosed physical condition? To identify which physical problems might create mental symptoms, start with Blake Graham's excellent checklist. PDF

If you are considering withdrawing from benzos, you will want the best information you can find. Withdrawal has to be done carefully to prevent causing further harm. Please check out this great guide - by benzodiazepine withdrawal expert Dr. Heather Ashton - it's FREE. http://www.benzo.org.uk/manual/

Dr. Ashton tells us what benzos do in the body - http://www.benzo.org.uk/manual/bzcha01.htm

Dr. Breggin writes about the effects of benzodiazepines on behavior and personality
http://www.benzo.org.uk/breggin.htm


Wikipedia has an article on long-term effects of benzodiazepine use - http://en.wikipedia.org/wiki/Long-term_effects_of_benzodiazepines

Supplementing GABA - a natural substance which benzos were designed to replace - may be a better solution - and may be right for many of us.
Margot Kidder is probably the best-known person who has overcome substance abuse and regained mental stability with GABA. Read about her recovery here -
http://www.alternativementalhealth.com/articles/aminobipolar.htm

GABA is available at the Life Extension Foundation - here.

Creative Aging With the Raging Grannies

The Raging Grannies "bared all" at the Creative Aging Symposium held in San Francisco, June 15, 2009.
Posing as the scheduled entertainment for the symposium, they took the stage and made the case for Single Payer Health Care Reform.

The Symposium was sponsored, in part, by an insurance company, and also gets funds from AARP which acts very much like a corporate insurance company and is against any health care reform that would eliminate insurance companies.

IN THE VIDEO: Some members of the crowd look suspicious, others sing along with the Grannies who croon, "We won't feed CEO's anymore!" to the tune of This Little Light of Mine.
Eight-minute QuickTime movie. 36MB at Link


Do you have the right stuff to be a Raging Granny?
Raging Grannies Net - with Song Lyrics
Some Raging Granny Songs
Raging Grannies Official Site
Raging Grannies Film Launch
Link to buy Raging Grannies CD
Link to buy Raging Grannies book

Mitochondrial Damage: Can it be repaired?

Yes.

Drugs designed to target one aspect of aging also seem to help repair DNA damage and regulate gene activity, preventing them from going haywire with the stresses of time.

"In principle, we now could have a way of reversing the effects of aging," said David Sinclair, a Harvard University gerontologist and co-founder of Sirtris Pharmaceuticals, a company best-known for its development of an experimental drug called resveratrol.
Resveratrol and similar compounds activate an enzyme called SIRT1. The enzyme rejuvenates mitochondria, the machines that power our cells. Mitochondrial breakdown has been associated with many age-related diseases, including heart disease, diabetes and dementia. Several labs in addition to Sirtris are researching compounds that target mitochondria.
The new findings suggest that SIRT1 fixes DNA in addition to mitochondria.

Sinclair's team found that unless SIRT1 enzymes gathered at sites where DNA had started to unravel, other DNA repair proteins failed to arrive. This allowed damage to progress, eventually causing dormant genes to come alive, a process called deregulation.
Some researchers think gene deregulation is a cause of aging: As cells get older, they produce less SIRT1, ostensibly becoming less able to repair faulty DNA and suppress the dormant genes.

But in mice either given resveratrol or genetically engineered to produce extra SIRT1 on their own, repairs went smoothly and quickly.
"One idea of why we age is that DNA becomes damaged or mutated," said Sinclair, lead author of the research published Wednesday in Cell. "But perhaps the main culprit is the effect of genes switching on and off, and that should be reversible."

Link


What to do? Detailed information for chronic fatigue patients but useful and informative for all to follow is in a pdf - here.
http://www.ijcem.com/files/IJCEM812001.pdf

Supplements of Alpha-lipoic acid, L-carnitine and Co-enzyme Q10 to restore mitrochondrial function http://articles.latimes.com/2008/aug/25/health/he-skeptic25

Scholarly articles on ALCAR treatment can be accessed at Mitochondrial.net, here.

One protocol in an individual with mitochondrial disease called for the following:
Alpha-lipoic Acid (ALA) 300 mg 2x/day
Co-Q-10 200 mg 2x/day
Creatine Monohydrate powder 2.5 gm 2x/day

Creativity, Aging and Brain Illnesses

Amazing art here
Found at Boing Boing.