Vitamin D has a significant biochemistry in the brain. Nuclear receptors for vitamin D exist in the brain and vitamin D is involved in the biosynthesis of neurotrophic factors, synthesis of nitric oxide synthase, and increased glutathione levels—all suggesting an important role for vitamin D in brain function. Animal data indicates that tyrosine hydroxylase, the rate-limiting enzyme for all the brain's monoamines, is increased by vitamin D. Rats born to severely vitamin D deficient dams have profound brain abnormalities.Link
Clearly this is an issue that affects us all! We ask about the most vulnerable - how many children, seniors and incarcerated persons are deficient in Vitamin D - and show abnormalities in behavior and thinking as a result?