Canada: Recipients of flu vaccine more likely to catch H1N1

From the page:

...according to Dr. Rubinstein, the research shows that people who received the seasonal shot during the 2007-08 flu season remained vulnerable to swine flu well into 2009 – an interval that should provide most immune systems ample restoration time.

“We don't understand the mechanism,” Dr. Rubinstein said. “At the present time it is quite perplexing.”

Link

Placebos are Getting More Effective - and Drugmakers are Desperate to Know Why

Article at WIRED Magazine

Misdiagnosed Youngsters? - John Sorboro, MD

Psychiatric News September 6, 2002
Volume 37 Number 17
© 2002 American Psychiatric Association
p. 32
Letter to the Editor

Misdiagnosed Youngsters?

John Sorboro, M.D.
Youngstown, Ohio

"It was with great interest that I read in your June 21 issue a review of the study by Dr. Barbara Geller, "Two-Year Prospective Follow-Up of Children With a Prepubertal and Early Adolescent Bipolar Disorder Phenotype." This study should be a wake-up call to the legions of psychiatrists who continue to pollute our youth with medications that have no real benefit or solid research to support there use.

I found it most puzzling that the author, while speculating why none of the "treatment" worked but a two-parent home was of benefit, did not consider the most obvious answer: that most of the children in her study (as well as in the United States) whom we call "bipolar" are not. Have we all forgotten what Kraepelin taught us, and how this illness is defined? The psychiatric community needs to recognize the limits of descriptive diagnosis with regard to both treatment and research. Most of us recognize there is a spectrum to this illness, but we must end this practice of labeling all children with mood lability and chaotic behavior—as well as adults with personality disorders—as bipolar.

I have cared for hundreds of adolescents in a residential setting who were diagnosed as bipolar, and many had reported psychotic symptoms. None of them was helped by medications that we acknowledge help adults with manic-depressive illness. Many of the youngsters improved with time because of structured environment and growth. Neuropsychiatric illnesses such as obsessive-compulsive disorder, major depression, and schizophrenia can present in young people, but let’s stop pretending that all behaviorally disordered children have an illness that by definition will never go away.

Have we also forgotten that our first job as physicians is to recognize our limits and to do no harm?"

Link

Was Bayer Aspirin Behind 1918 Flu Deaths?

"High aspirin dosing levels used to treat patients during the 1918-1919 pandemic are now known to cause, in some cases, toxicity and a dangerous build up of fluid in the lungs, which may have contributed to the incidence and severity of symptoms, bacterial infections, and mortality. Additionally, autopsy reports from 1918 are consistent with what we know today about the dangers of aspirin toxicity, as well as the expected viral causes of death.
The motivation behind the improper use of aspirin is a cautionary tale, said author Karen Starko, MD. In 1918, physicians did not fully understand either the dosing or pharmacology of aspirin, yet they were willing to recommend it. Its use was promoted by the drug industry, endorsed by doctors wanting to "do something," and accepted by families and institutions desperate for hope."
Link

More old ads can be seen here.

Game Brain

This article from Men Style/GQ is a little way off our usual Pharma trail, but certainly made us think - and wonder how many damaged brains we will see in the future in users of certain medications. The cruelty of corporate executives involved in these cases is noteworthy and clear; we do not doubt that similar coverups and indifference occur in fields other than sports.

"Let’s say you run a multibillion-dollar football league. And let’s say the scientific community—starting with one young pathologist in Pittsburgh and growing into a chorus of neuroscientists across the country—comes to you and says concussions are making your players crazy, crazy enough to kill themselves, and here, in these slices of brain tissue, is the proof. Do you join these scientists and try to solve the problem, or do you use your power to discredit them?"



"The coverage that week had been bracing and disturbing and exciting. Dead at 50. Mike Webster! Nine-time Pro Bowler. Hall of Famer. “Iron Mike,” legendary Steelers center for fifteen seasons. His life after football had been mysterious and tragic, and on the news they were going on and on about it. What had happened to him? How does a guy go from four Super Bowl rings to…pissing in his own oven and squirting Super Glue on his rotting teeth? Mike Webster bought himself a Taser gun, used that on himself to treat his back pain, would zap himself into unconsciousness just to get some sleep. Mike Webster lost all his money, or maybe gave it away. He forgot. A lot of lawsuits. Mike Webster forgot how to eat, too. Soon Mike Webster was homeless, living in a truck, one of its windows replaced with a garbage bag and tape.
...
Omalu stared at Mike Webster’s brain. He kept thinking, How did this big athletic man end up so crazy in the head? He was thinking about football and brain trauma. The leap in logic was hardly extreme. He was thinking, Dementia pugilistica? “Punch-drunk syndrome,” they called it in boxers. The clinical picture was somewhat like Mike Webster’s: severe dementia—delusion, paranoia, explosive behavior, loss of memory—caused by repeated blows to the head. Omalu figured if chronic bashing of the head could destroy a boxer’s brain, couldn’t it also destroy a football player’s brain? Could that be what made Mike Webster crazy?"

Article continues here.

The New York Times has more here.

Bipolar Disorder Secondary to Head Injury - a MEDLINE Search by Ivan K. Goldberg, M.D. can be found here.

To view healthy and sick brains at the Harvard Whole Brain Atlas, go here.

The Sports Legacy Institute is here.

Drug-Induced Dementia: The Perfect Crime

"Under the influence of declining birth rates, expanding longevity, and changing population structures around the world, the global prevalence of senile dementia is expected to increase more than four-fold within the next forty years. Within the United States alone, the number of affected individuals over the age of 65 is expected to rise exponentially from 8 million cases (2% of the entire population in the year 2000), to 18 million retirees (roughly 4.5% of the national census in the year 2040). Although they are striking, these statistics quite likely underestimate the scope of the coming epidemic, as they fail to consider the impact of under-diagnosis, early-onset disease, and the potential for a changing incidence of illness in the context of increasingly toxic environments.

In the face of this imminent crisis, concerned observers have called for policies and practices which aim to prevent, limit, or reverse dementia. Drug-Induced Dementia: A Perfect Crime is a timely resource which reveals why and how medical treatments themselves – specifically, psychopharmaceuticals – are a substantial cause of brain degeneration and premature death.

A first-of-its-kind resource for patients and clinicians, the book integrates research findings from epidemiology (observational studies of patients in the “real world”), basic biology (animal experiments), and clinical science (neuroimaging and autopsy studies) in order to demonstrate the dementing and deadly effects of psychiatric drugs.

Highlighted by more than 100 neuroimages, slides of tissue specimens, and illustrations, the book uniquely describes:

Ø the societal roots of the problem
(target organ toxicity, regulatory incompetence, and performativity)

Ø the subtypes and essential causes of dementia

Ø the patterns, prevalence, and causes of dementia associated with antidepressants, antipsychotics, anxiolytics, mood stabilizers, and stimulants

and

Ø the actions and reforms which patients, providers, and policy makers might immediately pursue, in an effort to mitigate the causes and consequences of this iatrogenic tragedy."

Link

The Quickening Maze

Mental Health in Fiction

The asylum in the forest
Andrew Motion applauds a vividly sympathetic exploration of poetry, madness and identity

Andrew Motion
The Guardian, Saturday 2 May 2009

High Beach, on the edge of Epping Forest in Essex, is a strange poetic vortex. Wilfred Owen and Edward Thomas were stationed there during the first world war; we have no evidence that they met. Seventy-odd years earlier, a better-known literary overlap occurred in the same vicinity, thanks to one Matthew Allen. Allen was founder of the High Beach Private Asylum, the institution that first gave shelter to John Clare. He was also a friend of Alfred Tennyson, doctor to Tennyson's brother Septimus, and eventually (by persuading them to put money into a half-baked wood-carving scheme) the cause of their bankruptcy. You wouldn't know any of this today, driving through the Epping commuter belt, but it's a resonant place for literary archaeologists.

The Quickening Maze has been shortlisted for the Booker Prize.
Link




I am: yet what I am none cares or knows,
My friends forsake me like a memory lost;
I am the self-consumer of my woes,
They rise and vanish in oblivious host,
Like shades in love and death's oblivion lost;
And yet I am! and live with shadows tost

Into the nothingness of scorn and noise,
Into the living sea of waking dreams,
Where there is neither sense of life nor joys,
But the vast shipwreck of my life's esteems;
And e'en the dearest--that I loved the best--
Are strange--nay, rather stranger than the rest.

I long for scenes where man has never trod;
A place where woman never smil'd or wept;
There to abide with my creator, God,
And sleep as I in childhood sweetly slept:
Untroubling and untroubled where I lie;
The grass below--above the vaulted sky.

~ John Clare

Is mental health an occupational hazard of poets? Link

We think the problem is nutritional; once that weakness is mended, the individual remains creative - and is well.